Patty Spears

PREDICT-RD: Postoperative molecular residual disease by ctDNA surveillance in TNBC with residual disease (TBCRC-071).

Yara Abdou, Naim Rashid, Katherine Elizabeth Reeder-Hayes, Allison Camp et autres

TPS647 Background: Patients with residual triple-negative breast cancer (TNBC) post-neoadjuvant therapy, particularly those with higher residual cancer burden (RCB II/III), remain at high risk of recurrence despite standard adjuvant therapy. Current post-treatment surveillance relies primarily on clinical follow-up and imaging, which have …

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Effects of ovarian ablation or suppression on breast cancer recurrence and survival: patient-level meta-analysis of 15 000 women in 23 randomised trials

Rosie Bradley, Jeremy Braybrooke, Mike J Clarke, Robert K. Hills et autres

BACKGROUND: For premenopausal women with oestrogen receptor (ER)-positive early breast cancer, the additional protective effect of ovarian function suppression (OFS, by ablation or drugs) may depend on menopausal status after any chemotherapy, and tamoxifen usage. We assess the effects of OFS on …