Vitamin D receptor isoform VDRA suppresses hepatocellular tumorigenesis by restricting YAP nuclear localization
Li Li, Shiwei He, Ruoya Wang, Jianbin Wang et autres
Hepatocellular carcinoma (HCC) frequently arises from uncontrolled proliferation of hepatocyte epithelium, a process potently driven by the transcriptional regulator yes-associated protein (YAP). Although 1,25(OH)₂D₃, the active form of vitamin D, exerts established anti-proliferative effects through its receptor (VDR), the specific roles of …
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Cell Death and Disease