Emergence of Plasmodium falciparum pfdhps A581G mutation in Southern Senegal under Seasonal Malaria Chemoprevention pressure, 2020-2023
Mamadou Alpha Diallo, Abdoulaye Tine, Djiby Sow, Aita Sene et autres
Malaria prevention in Senegal includes the use of Seasonal Malaria Chemoprevention with sulfadoxine-pyrimethamine plus amodiaquine. Prolonged use of sulfadoxine-pyrimethamine, however, can select for mutations in the Plasmodium falciparum mutations in pfdhfr and pfdhps genes. We analyse dried-blood-spot samples collected during therapeutic-efficacy studies …
Sénégal (code pays fourni par la source)
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Communications Medicine