104 Molecular Subgroups of IDH Wild-Type Glioblastoma Exhibit Distinct Treatment Responses to Resection and Adjuvant Therapy, a Multi-Institutional Study
Zachary C. Gersey, Arka N. Mallela, Jacob Young, Daniel Quintana et autres
INTRODUCTION: IDH wild-type glioblastoma (GBM) remains a clinically heterogeneous disease with poor survival outcomes. Prior molecular subclassification schemes lack clinical utility. Here, we use semi-supervised consensus clustering to identify molecular subtypes with distinct prognoses and treatment responses. METHODS: Eight hundred and fifty-eight …
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Neurosurgery