A dual role of EZH2 in regulating A-to-I RNA editing and mRNA stability through ADAR
Yang Yi, Yanqiang Li, Rui Wang, Xufen Yu et autres
Adenosine-to-inosine (A-to-I) RNA editing, catalyzed by adenosine deaminases acting on RNA (ADARs), is a widespread modification in metazoans. Cumulative evidence has revealed the altered A-to-I editing profiles in cancers, but the underlying mechanism remains unclear. Here, we discover the well-known histone lysine …
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