Inhibition of mitochondrial ROS turns LC3-associated phagocytosis to autophagy upon resveratrol treatment for group A Streptococcus clearance in endothelial cells
Yi-Lin Cheng, Marcia Shu-Wei Su, Chen-Chieh Liao, Ting-Wei Chang et autres
Group A Streptococcus (GAS; Streptococcus pyogenes ), which causes a broad spectrum of diseases, has been found to invade cells to avoid host immune clearance and antibiotic killing. Our previous findings have shown that the virulence factors of GAS—NAD-glycohydrolase depletes intracellular NAD …
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Journal of Microbiology Immunology and Infection