Development and validation of a 2-step shared parameter model for dementia imputation in the Cardiovascular Health Study cohort
Katie M. Lynch, Erin E. Bennett, Chelsea Liu, Emma K. Stapp et autres
BACKGROUND: Large-scale dementia ascertainment for research remains challenging. We demonstrate a method to impute dementia status and onset time using data from the Cardiovascular Health Study (CHS). METHODS: We used a linear mixed-effects model to estimate individual cognitive trajectories and included the …
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The Journals of Gerontology Series A