Michael Holzer

Observational study: Temporal dynamics of lipoprotein(a) after out-of-hospital cardiac arrest

Daniel Kogler, Christian Schoergenhofer, Alexandra Lipa, Luca Kurz et autres

Background: Out-of-hospital cardiac arrest (OHCA) is a major cause of death in the USA and Europe, with survival rates around 10%. Lipoprotein (a) [Lp(a)] is an established cardiovascular risk factor, but its temporal profile following OHCA is unknown. Methods: In this retrospective …

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Post-resuscitation left ventricular dysfunction in a rat model of ventricular fibrillation and extracorporeal cardiopulmonary resuscitation

Wolfgang Weihs, Matthias Mueller, Ingrid Anna Maria Magnet, Alexander Franz Szinovatz et autres

While the majority of rodent resuscitation studies prioritize neurologic outcomes, research into the long-term effects of global ischemia and reperfusion on cardiac function is scarce, generally limited to morphologic assessments. Extracorporeal cardiopulmonary resuscitation (ECPR) is a promising strategy for highly selected patients …

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Mitochondrial dysfunction upon impaired oxygen delivery: cardiac arrest versus hemorrhagic shock

Sergejs Zavadskis, Alexander Franz Szinovatz, Sergiu Dumitrescu, Sarolta Takacs et autres

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The First Hour After ROSC: Impact Of Early Ventilation And Gas Exchange On Neurologic Outcome After Cardiac Arrest

Karolína Valentová, Roman Brock, Alexandra Julia Lipa, Andrea Kornfehl et autres

Background Cardiac arrest remains associated with high mortality and neurological morbidity. The early post-resuscitation phase is critical for cerebral recovery – ventilatory management may represent a modifiable determinant of outcome. Methods We performed a retrospective analysis of adult patients admitted to the …

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When controls are healthy: the difficulty of testing neuroprotection in low-injury models

Wilhelm Behringer, Benjamin Abella, Jasmin Arrich, Bernd Walter Boettiger et autres

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On-scene selective brain cooling in ventricular fibrillation cardiac arrest: pilot results from the PRINCESS2 randomised trial

Emelie Dillenbeck, Thomas Berthelsen, Ervigio Corral Torres, Esteban Lopez-de-Sa et autres

BACKGROUND: Although ischemia-reperfusion brain injury represents a major clinical problem after cardiac arrest, no neuroprotective treatment currently exists. The PRINCESS2 trial is designed to confirm previous findings, indicating that on-scene selective brain cooling using a portable trans-nasal cooling method improves complete neurological …

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On-scene selective brain cooling in ventricular fibrillation cardiac arrest: pilot results from the PRINCESS2 randomised trial

Emelie Dillenbeck, Thomas Berthelsen, Ervigio Corral Torres, Esteban Lopez-de-Sa et autres

Abstract Background Although ischemia-reperfusion brain injury represents a major clinical problem after cardiac arrest, no neuroprotective treatment currently exists. The PRINCESS2 trial is designed to confirm previous findings, indicating that on-scene selective brain cooling using a portable trans-nasal cooling method improves complete …

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On-scene selective brain cooling in ventricular fibrillation cardiac arrest: pilot results from the PRINCESS2 randomised trial

Emelie Dillenbeck, Thomas Berthelsen, Ervigio Corral Torres, Esteban Lopez-de-Sa et autres

Abstract Background Although ischemia-reperfusion brain injury represents a major clinical problem after cardiac arrest, no neuroprotective treatment currently exists. The PRINCESS2 trial is designed to confirm previous findings, indicating that on-scene selective brain cooling using a portable trans-nasal cooling method improves complete …

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Additional file 1 of On-scene selective brain cooling in ventricular fibrillation cardiac arrest: pilot results from the PRINCESS2 randomised trial

Emelie Dillenbeck, Thomas Berthelsen, Ervigio Corral Torres, Esteban Lopez-de-Sa et autres

Supplementary Material 1

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Additional file 1 of On-scene selective brain cooling in ventricular fibrillation cardiac arrest: pilot results from the PRINCESS2 randomised trial

Emelie Dillenbeck, Thomas Berthelsen, Ervigio Corral Torres, Esteban Lopez-de-Sa et autres

Supplementary Material 1

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Temporal Dynamics of Lipoprotein(a) After Out-of-Hospital Cardiac Arrest

Daniel Kogler, Alexandra Lipa, Magdalena Boegl, Luca Kurz et autres

Chest Compression Synchronised Ventilation (CCSV) versus Intermittent Positive-Pressure Ventilation (IPPV) During Out-of-Hospital Cardiac Arrest: A Randomized Controlled Trial

Sebastian Schnaubelt, Daniela Rodrigues Recchia, Patrick Aigner, Roman Brock et autres

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