Supplementary material from "Histidine and Tyrosine Residues are Targets for SIRT6 ADP-ribosylation Activity"
J.G.M. Rack, Evgeniia Prokhorova, R. Lauro, Anna Georgina Kopasz et autres
SIRT6, a highly conserved member of the sirtuin family, plays a critical role in diverse cellular processes, including gene regulation, DNA damage response, and maintaining nuclear lamina integrity. These functions are essential in contexts such as differentiation, metabolic regulation, cancer development, and …