Accès ouvert
2026
article
OpenAlex
Danny Arends, David G. Ashbrook, Suheeta Roy, Lu Lu et autres
DNA variants modulate mortality risks across an entire lifespan but their dynamic age-dependent effects have not been resolved in any species for either sex. Here we mapped variants that shape mortality using an actuarial approach, starting with a base population of 6,438 …
Accès ouvert
2025
article
OpenAlex
Charlotte G. Mann, Michael Robert MacArthur, Jing Zhang, Songlin Gong et autres
Dietary restriction of the sulfur-containing amino acids methionine and cysteine (SAAR) has numerous metabolic benefits including enhanced body composition and insulin sensitivity. Many of these benefits parallel those associated with endurance exercise. How SAAR impacts skeletal muscle remains largely unexplored. Here, we …