Optimizing T cell responses of targeted peptide antigen delivery by modulating antigen processing through amino acid exchange
Ida Laurén, Alexandros Kostakis, Martin Lord, Elvira Björklund et autres
Antibody-drug conjugates have demonstrated enhanced efficacy and reduced toxicity by targeted delivery of toxic payloads, yet they can also be used to deliver non-toxic payloads (peptides and oligonucleotides) tailored for disease-specific needs. We have previously developed an adaptable drug conjugate strategy using …
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International Journal of Biological Macromolecules