PAF15 drives melanoma progression by promoting proliferation concomitant with suppression of DNA damage and apoptosis: a novel therapeutic vulnerability
Yacong Ji, Chongyang Li, Han Hao, Yang Liu et autres
PAF15 is an oncogene and is overexpressed across multiple malignancies. However, its biological role in melanoma remains largely unclear. In this research, bioinformatics analysis (GEPIA2, TCGA, CancerSEA) confirmed transcriptional PAF15 overexpression in melanoma, correlating with a poor prognosis and implicating pathways involved …
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