Mixed-model and transcriptome-wide association analyses identify transcription factors and genes associated with colorectal cancer susceptibility
Z.W. Chen, Wenqiang Song, Qing Li, Chao Li et autres
Susceptibility transcription factors (TF) whose DNA bindings are altered by genetic variants regulating colorectal cancer (CRC) risk genes remain poorly defined. Using generalized linear mixed models, we analyze 218 TF ChIP-Seq datasets alongside GWAS data from 100,204 CRC cases and 154,587 controls …
us, gb, es, dk, kr, cn, jp (code pays fourni par la source)
2 citations
Nature Communications