In vivo evidence for bleb-induced survival signaling in metastatic melanoma
Andrew Weems, Md Torikul Islam, Hazel Borges, Clarence Yapp et autres
Bleb signaling is a cellular process in which pressure-driven plasma membrane protrusions generate localized micron-scale membrane curvature that recruits cytosolic septin complexes, assembling signaling hubs that promote cell survival. Our prior work showed that this morphology-encoded signaling pathway is necessary to sustain …
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2 citations
bioRxiv (Cold Spring Harbor Laboratory)