Monitoring of CNS involvement in AML using ultrahigh-sensitivity next-generation sequencing of cell-free DNA
Henri C. Hupe, Sophie Pietzka, Clara Wienecke, Stephan Bartels et autres
Abstract Introduction Evaluation and monitoring of central nervous system (CNS) involvement in AML patients with standard of care methods (cytomorphology, flow cytometry) is limited, as they require sufficient cell numbers in the cerebrospinal fluid (CSF). To date, no method is available for …
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