Accès ouvert
2026
article
OpenAlex
Alberto Polo-Barranco, Carlos Rebolledo-Maldonado, Dairo Rodelo-Barrios, Juan Solano-Ropero et autres
Elevated plasma lipoprotein(a) [Lp(a)] levels represent a predominantly genetically determined risk factor for atherosclerotic cardiovascular disease and calcific aortic valve disease (CAVD). Mechanistically, Lp(a) transports oxidized phospholipids, lysophosphatidylcholine, and autotaxin, components capable of promoting inflammation, oxidative stress, and valvular fibrocalcific remodeling. This …
co
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Accès ouvert
2026
preprint
OpenAlex
Alberto Polo-Barranco, Carlos Rebolledo-Maldonado, Dairo Rodelo-Barrios, Juan Solano-Ropero et autres
Lipoprotein(a) [Lp(a)] is a predominantly genetic risk factor for atherosclerotic cardiovascular disease and calcified aortic valve disease (CAVD). In addition to its epidemiological and genetic association with aortic stenosis, Lp(a) transports oxidized phospholipids, lysophosphatidylcholine, and autotaxin, components capable of promoting inflammation, oxidative …
Accès ouvert
2025
article
OpenAlex
Alberto Polo-Barranco, Carlos Rebolledo-Maldonado, Valeria Esquiaqui-Rangel, Andrea Nuñez-Mejia et autres
Even when people with diabetes mellitus (DM) meet their cholesterol goals, they still face a higher risk of heart and blood vessel problems. One major reason is a particle called lipoprotein(a), or Lp(a), which is similar to LDL cholesterol. Raised levels of …
co
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
Alberto Polo-Barranco, Carlos Rebolledo-Maldonado, Valeria Esquiaqui-Rangel, Andrea Nuñez-Mejia et autres
Diabetes mellitus (DM) is associated with a residual cardiovascular risk that persists even when lipid targets are achieved. Within this context, lipoprotein(a) [Lp(a)], an LDL-like particle of genetic origin with pro-atherogenic and antifibrinolytic properties, emerges as a key determinant in the progression …
co
(code pays fourni par la source)