Mapping the temporal and functional landscape of Sonic Hedgehog signaling reveals new insights into early human forebrain development
Veranika Panasenkava, Jules Garreau, Hélène Guyodo, Farah Diab et autres
SUMMARY The early patterning of the anterior neuroectoderm constitutes a fundamental blueprint for human brain development, orchestrated by multiple signaling pathways. Among them, Sonic Hedgehog (SHH) plays a key influence. However, the transcriptional programs it engages remain poorly defined due to the …
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bioRxiv (Cold Spring Harbor Laboratory)