Profil bibliographique

Rik J. Scheper

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

516Publications signalées

34471Citations signalées

0Affiliations récentes

Les domaines associés

Immunotherapy and Immune ResponsesDrug Transport and Resistance MechanismsT-cell and B-cell ImmunologyImmune Cell Function and InteractionCAR-T cell therapy research

Les publications récentes

Accès ouvert 2023 other OpenAlex

Table S2 from Melanoma Sequentially Suppresses Different DC Subsets in the Sentinel Lymph Node, Affecting Disease Spread and Recurrence

Mari F.C.M. van den Hout, Bas D. Koster, Berbel J.R. Sluijter, Barbara G. Molenkamp et autres

SLN characteristics of patients with 2 SLNs

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Accès ouvert 2023 other OpenAlex

Figure S6 from Melanoma Sequentially Suppresses Different DC Subsets in the Sentinel Lymph Node, Affecting Disease Spread and Recurrence

Mari F.C.M. van den Hout, Bas D. Koster, Berbel J.R. Sluijter, Barbara G. Molenkamp et autres

Differences in SLN-resident DCs between patients with and without distant recurrence

0 citations

Accès ouvert 2023 other OpenAlex

Figure S5 from Melanoma Sequentially Suppresses Different DC Subsets in the Sentinel Lymph Node, Affecting Disease Spread and Recurrence

Mari F.C.M. van den Hout, Bas D. Koster, Berbel J.R. Sluijter, Barbara G. Molenkamp et autres

Differences in frequency and phenotype of skin-derived SLN DCs between patients with and without local recurrence

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Accès ouvert 2023 other OpenAlex

Table S1 from Melanoma Sequentially Suppresses Different DC Subsets in the Sentinel Lymph Node, Affecting Disease Spread and Recurrence

Mari F.C.M. van den Hout, Bas D. Koster, Berbel J.R. Sluijter, Barbara G. Molenkamp et autres

Placebo-administered vs off-trial patients

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Accès ouvert 2023 supplementary-materials OpenAlex

Supplementary Figure 1 from Arming the Melanoma Sentinel Lymph Node through Local Administration of CpG-B and GM-CSF: Recruitment and Activation of BDCA3/CD141+ Dendritic Cells and Enhanced Cross-Presentation

Berbel J.R. Sluijter, Mari F.C.M. van den Hout, Bas D. Koster, Paul A.M. van Leeuwen et autres

Gating strategies for analysis of A) plasmacytoid DC (pDC) and B) skin-migratory conventional DC (cDC) subsets: Dermal DC (DDC) and Langerhans Cells (LC) and C) LN-resident cDC subsets in melanoma Sentinel Lymph Nodes (SLN).

0 citations

Accès ouvert 2023 other OpenAlex

Data from Melanoma Sequentially Suppresses Different DC Subsets in the Sentinel Lymph Node, Affecting Disease Spread and Recurrence

Mari F.C.M. van den Hout, Bas D. Koster, Berbel J.R. Sluijter, Barbara G. Molenkamp et autres

Abstract Melanoma exerts immune-suppressive effects to facilitate tumor progression and metastatic spread. We studied these effects on dendritic cell (DC) and T-cell subsets in 36 melanoma sentinel lymph node (SLN) from 28 stage I–III melanoma patients and determined their clinical significance. Four …

0 citations

Accès ouvert 2023 other OpenAlex

Data from Arming the Melanoma Sentinel Lymph Node through Local Administration of CpG-B and GM-CSF: Recruitment and Activation of BDCA3/CD141+ Dendritic Cells and Enhanced Cross-Presentation

Berbel J.R. Sluijter, Mari F.C.M. van den Hout, Bas D. Koster, Paul A.M. van Leeuwen et autres

Abstract Melanoma-induced suppression of dendritic cells (DC) in the sentinel lymph node (SLN) interferes with the generation of protective antitumor immunity. In an effort to strengthen immune defense against metastatic spread, we performed a three-arm phase II study comprising 28 patients with …

0 citations

Accès ouvert 2023 other OpenAlex

Figure S1 from Melanoma Sequentially Suppresses Different DC Subsets in the Sentinel Lymph Node, Affecting Disease Spread and Recurrence

Mari F.C.M. van den Hout, Bas D. Koster, Berbel J.R. Sluijter, Barbara G. Molenkamp et autres

Flowcytometric gating strategies for regulatory T cells in the melanoma sentinel lymph node and correlation between Treg frequencies in the melanoma SLN as measured by FoxP3 or by CTLA4 expression

0 citations

Accès ouvert 2023 other OpenAlex

Figure S3 from Melanoma Sequentially Suppresses Different DC Subsets in the Sentinel Lymph Node, Affecting Disease Spread and Recurrence

Mari F.C.M. van den Hout, Bas D. Koster, Berbel J.R. Sluijter, Barbara G. Molenkamp et autres

Major leukocyte subset frequencies in melanoma SLN grouped by stage

0 citations

Accès ouvert 2023 other OpenAlex

Figure S4 from Melanoma Sequentially Suppresses Different DC Subsets in the Sentinel Lymph Node, Affecting Disease Spread and Recurrence

Mari F.C.M. van den Hout, Bas D. Koster, Berbel J.R. Sluijter, Barbara G. Molenkamp et autres

CD4+CD25hiFoxP3+ Treg rates in melanoma SLN, grouped by tumor stage

0 citations

Accès ouvert 2023 other OpenAlex

Figure S2 from Melanoma Sequentially Suppresses Different DC Subsets in the Sentinel Lymph Node, Affecting Disease Spread and Recurrence

Mari F.C.M. van den Hout, Bas D. Koster, Berbel J.R. Sluijter, Barbara G. Molenkamp et autres

Flowcytometric gating strategies for dendritic cells in the melanoma sentinel lymph node

0 citations

Accès ouvert 2023 supplementary-materials OpenAlex

Supplementary Figure 2 from Arming the Melanoma Sentinel Lymph Node through Local Administration of CpG-B and GM-CSF: Recruitment and Activation of BDCA3/CD141+ Dendritic Cells and Enhanced Cross-Presentation

Berbel J.R. Sluijter, Mari F.C.M. van den Hout, Bas D. Koster, Paul A.M. van Leeuwen et autres

Expression of the cross-priming associated markers BDCA3/CD141 and CLEC9A on the four identified cDC subsets in single-cell suspensions of untreated melanoma Sentinel Lymph Nodes SLN (mean {plus minus} SEM of at least three separate experiments are shown).

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