Profil bibliographique

Esther Opoku

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

2Publications signalées
38Citations signalées
2Affiliations récentes

Les institutions déclarées

Cleveland State UniversityCleveland Clinic Lerner College of Medicine

Les domaines associés

Inflammasome and immune disordersAdvanced Glycation End Products researchAlcohol Consumption and Health EffectsHeme Oxygenase-1 and Carbon MonoxideDiet, Metabolism, and Disease

Les publications récentes

Accès ouvert 2024 article OpenAlex

Disulfiram Reduces Atherosclerosis and Enhances Efferocytosis, Autophagy, and Atheroprotective Gut Microbiota in Hyperlipidemic Mice

Cynthia Alicia Traughber, Kara Timinski, Ashutosh Prince, Nilam Bhandari et autres

Background Pyroptosis executor GsdmD (gasdermin D) promotes atherosclerosis in mice and humans. Disulfiram was recently shown to potently inhibit GsdmD, but the in vivo efficacy and mechanism of disulfiram's antiatherosclerotic activity is yet to be explored. Methods and Results We used human/mouse …

us (code pays fourni par la source)

34 citations Journal of the American Heart Association
Accès ouvert 2023 preprint OpenAlex

Disulfiram reduces atherosclerosis and enhances efferocytosis, autophagy, and atheroprotective gut microbiota in hyperlipidemic mice

Cynthia Alicia Traughber, Kara Timinski, Ashutosh Prince, Nilam Bhandari et autres

Abstract Pyroptosis executor Gasdermin (GsdmD) promotes atherosclerosis in mice and humans. Disulfiram (DSF) was recently shown to potently inhibit GsdmD, but the in-vivo efficacy and mechanism of DSF’s anti-atherosclerotic activity is yet to be explored. We used human/mouse macrophages and a hyperlipidemic …

us (code pays fourni par la source)

4 citations bioRxiv (Cold Spring Harbor Laboratory)
Notice OpenAlex

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