Kris Varney

Characterization and validation of EHR computable phenotypes for Long COVID using patient-reported symptoms: insights from the nationwide RECOVER program

Victor M Castro, Vivian Gainer, Nich Wattanasin, Andrew Cagan et autres

OBJECTIVE: Long COVID (LC) remains poorly understood, and there is a critical need for advanced computational tools to better identify and characterize patients. In this study, we use summarized symptom reports by RECOVER-Adult cohort participants linked to EHR data to characterize patients …

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Olfactory Dysfunction After SARS-CoV-2 Infection in the RECOVER Adult Cohort

Leora I. Horwitz, Jacqueline Becker, Weixing Huang, Teresa Akintonwa et autres

Importance: Olfactory dysfunction is common after SARS-CoV-2 infection and has been associated with cognitive loss in other conditions. Formal testing is needed to characterize the presence, severity, and patterns of olfactory dysfunction. Objective: To characterize long-term olfactory dysfunction after SARS-CoV-2 infection. Design, …

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Sex Differences in Long COVID

Dimpy P. Shah, Tanayott Thaweethai, Elizabeth W. Karlson, Hector Bonilla et autres

Importance: A substantial number of individuals worldwide experience long COVID, or post-COVID condition. Other postviral and autoimmune conditions have a female predominance, but whether the same is true for long COVID, especially within different subgroups, is uncertain. Objective: To evaluate sex differences …

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2024 Update of the RECOVER-Adult Long COVID Research Index

Linda N. Geng, Kristine M. Erlandson, Mady Hornig, Rebecca Letts et autres

Importance: Classification of persons with long COVID (LC) or post-COVID-19 condition must encompass the complexity and heterogeneity of the condition. Iterative refinement of the classification index for research is needed to incorporate newly available data as the field rapidly evolves. Objective: To …

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Measurement of circulating viral antigens post-SARS-CoV-2 infection in a multicohort study

Zoe Swank, Ella Borberg, Yulu Chen, Yasmeen Senussi et autres

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Differentiation of Prior SARS-CoV-2 Infection and Postacute Sequelae by Standard Clinical Laboratory Measurements in the RECOVER Cohort

Kristine M. Erlandson, Caitlin Selvaggi, Tanayott Thaweethai, Peter Chen et autres

BACKGROUND: There are currently no validated clinical biomarkers of postacute sequelae of SARS-CoV-2 infection (PASC). OBJECTIVE: To investigate clinical laboratory markers of SARS-CoV-2 and PASC. DESIGN: Propensity score-weighted linear regression models were fitted to evaluate differences in mean laboratory measures by prior …

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