Scott T. Weiss

Early-Life Factors and Body Mass Index Trajectories Among Children in the ECHO Cohort

Chang Liu, Sy‐Miin Chow, Izzuddin M. Aris, Dana Dabelea et autres

Importance: Identifying atypical body mass index (BMI) trajectories in children and understanding associated, modifiable early-life factors may help prevent childhood obesity. Objective: To characterize multiphase BMI trajectories in children and identify associated modifiable early-life factors. Design, Setting, and Participants: This cohort study …

us (code pays fourni par la source)

Exploring the Varied Clinical Presentation of Pediatric Asthma through the Metabolome

Kevin M. Mendez, Priyadarshini Kachroo, Nicole Prince, Mengna Huang et autres

Abstract Rationale Pediatric asthma is heterogeneous, with varied clinical presentations and treatment responses. Metabolomic profiling may uncover shared and unique biological mechanisms across clinical traits that characterize pediatric asthma. Objectives To characterize the varied clinical presentation of pediatric asthma by examining the …

au, us, dk, cr, se (code pays fourni par la source)

Associations between a novel measure of sleep health and cognitive functioning in middle childhood: a crosssectional Environmental Influences on Child Health Outcomes cohort study

Matthew C. Ferrell, Yingjia Wei, Kelly Glazer Baron, Courtney K. Blackwell et autres

Abstract Study Objectives Research linking children’s sleep to cognitive outcomes is inconsistent and has largely focused on one aspect of sleep, such as duration, rather than measuring multiple dimensions of sleep health. We hypothesized that children’s sleep health would be positively associated …

us (code pays fourni par la source)

Clinical effectiveness and safety of dupilumab in patients with chronic obstructive pulmonary disease: A 7-year population-based cohort study

Chuan-Yen Sun, Yohannes Tesfaigzi, Gin-Yi Lee, Yi-Hsuan Chen et autres

tw, us (code pays fourni par la source)

Genomewide Association between GLCCI1 and Response to Glucocorticoid Therapy in Asthma

Kelan G. Tantisira, Jessica Ann Lasky-Su, Michishige Harada, Amy Murphy et autres

BACKGROUND: The response to treatment for asthma is characterized by wide interindividual variability, with a significant number of patients who have no response. We hypothesized that a genomewide association study would reveal novel pharmacogenetic determinants of the response to inhaled glucocorticoids. METHODS: …

us (code pays fourni par la source)

A Genomewide Search for Quantitative-Trait Loci Underlying Asthma

Xin Ping Xu, Binyan Wang, Changzhong Chen, Wenwei Guang et autres

us, cn (code pays fourni par la source)