Profil bibliographique

Abigail Seaward

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

2Publications signalées
118Citations signalées
1Affiliations récentes

Les institutions déclarées

St George’s University Hospitals NHS Foundation Trust

Les domaines associés

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchInflammatory Bowel DiseaseHeparin-Induced Thrombocytopenia and Thrombosis

Les publications récentes

Accès ouvert 2022 article OpenAlex

Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study

Zhigang Liu, Kaixing Le, Xin Zhou, James L. Alexander et autres

BACKGROUND: Anti-TNF drugs, such as infliximab, are associated with attenuated antibody responses after SARS-CoV-2 vaccination. We aimed to determine how the anti-TNF drug infliximab and the anti-integrin drug vedolizumab affect vaccine-induced neutralising antibodies against highly transmissible omicron (B.1.1.529) BA.1, and BA.4 and …

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36 citations ˜The œLancet. Gastroenterology & hepatology
Accès ouvert 2022 article OpenAlex

Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab

Simeng Lin, Nicholas A. Kennedy, Aamir Saifuddin, Diana Mūnoz Sandoval et autres

Anti tumour necrosis factor (anti-TNF) drugs increase the risk of serious respiratory infection and impair protective immunity following pneumococcal and influenza vaccination. Here we report SARS-CoV-2 vaccine-induced immune responses and breakthrough infections in patients with inflammatory bowel disease, who are treated either …

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82 citations Nature Communications
Notice OpenAlex

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