Hiromi Sumita

Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1

Hisano Yajima, Yuki Anraku, Yu Kaku, Kanako Kimura et autres

Since 2019, SARS-CoV-2 has undergone mutations, resulting in pandemic and epidemic waves. The SARS-CoV-2 spike protein, crucial for cellular entry, binds to the ACE2 receptor exclusively when its receptor-binding domain (RBD) adopts the up-conformation. However, whether ACE2 also interacts with the RBD …

jp, cz (code pays fourni par la source)

A triggering structure of SARS-CoV-2 BA.2.86 spike upon ACE2 binding for receptor-binding domain up

Takao Hashiguchi, Hisano Yajima, Yuki Anraku, Yu Kaku et autres

Abstract Since 2019, SARS-CoV-2 has undergone mutations, resulting in pandemic and epidemic waves. The SARS-CoV-2 spike protein, crucial for cellular entry, is believed to bind to the ACE2 receptor exclusively when its receptor-binding domain (RBD) adopts the “up” conformation. However, whether ACE2 …

jp, gb (code pays fourni par la source)

Mammary gland growth and response to hormones in mastomys compared with mice.

H. Nagasawa, U Koshimizu, Minoru Watanabe, Kazuya TOKUDA et autres

Mammary gland growth with or without hormone manipulation was examined in virgin mastomys (Praomys (mastomys) natalensis) and compared with C3H/He mice having a low mammary tumor incidence. Mammary glands of mastomys consisted mostly of duct systems even at 720 days of age, …

jp (code pays fourni par la source)

General lectures (II)

Kose Segawa, Saburo Nakazawa, Naohiko Koide, Kenji Imai et autres

jp (code pays fourni par la source)

Relationship between glucose and lipid metabolism in rat liver (V) With special reference to glyceraldehyde-3-phosphate dehydrogenase

Tadataka Mizoguchi, Hiroshi Nomoto, Koichiro Ishida, C. Misaki et autres

jp (code pays fourni par la source)