High-dimensional single-cell definition of CLL T cells identifies Galectin-9 as novel immunotherapy target
Laura Llaó Cid, JKL Wong, Iria Fernandez Botana, Yashna Paul et autres
Abstract Failure of cancer immunotherapy is linked to T cell exhaustion. To decipher the underlying mechanisms, we explored the T cell landscape in blood, bone marrow and lymph node samples of patients with chronic lymphocytic leukemia (CLL), and spleen samples of a …
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6 citations
bioRxiv (Cold Spring Harbor Laboratory)