Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk
Felix R. Day, Deborah J. Thompson, Hannes Helgason, Daniel I. Chasman et autres
The timing of puberty is a highly polygenic childhood trait that is epidemiologically associated with various adult diseases. Using 1000 Genomes Project-imputed genotype data in up to ∼370,000 women, we identify 389 independent signals (P < 5 × 10(-8)) for age at …
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White Rose Research Online (University of Leeds, The University of Sheffield, University of York)