Accès ouvert
2026
article
OpenAlex
Lauren Lajos, Balotin Fogang, Anne Jensen, Derrick Hyacinthe Nyasse Atchombat et autres
Asymptomatic carriage of Plasmodium falciparum is a major public health threat hindering malaria eradication. Many areas with ongoing malaria transmission are coendemic for soil-transmitted helminths (STHs). Proteins secreted by helminths can regulate host inflammatory immune responses as a survival strategy. Given that …
us, Cameroun, gb
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Lauren Lajos, Balotin Fogang, Anne Jensen, Derrick Hyacinthe Nyasse Atchombat et autres
Abstract Description Asymptomatic Plasmodium carriage poses a major public health threat, hindering malaria eradication, yet the mechanisms governing this phenomenon remain unclear. Many LMICs are endemic for both malaria and soil-transmitted helminths (STH). Helminths are known to secrete various proteins during infection …
us, Cameroun
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Amanda Mixon Blackwell, Yasaman Jami‐Alahmadi, Armiyaw Sebastian Nasamu, Shota Kudo et autres
Malaria parasites have evolved unusual metabolic adaptations that specialize them for growth within heme-rich human erythrocytes. During blood-stage infection, Plasmodium falciparum parasites internalize and digest abundant host hemoglobin within the digestive vacuole. This massive catabolic process generates copious free heme, most of …
us, jp, ru
(code pays fourni par la source)
Accès ouvert
2024
peer-review
OpenAlex
Amanda Mixon Blackwell, Yasaman Jami‐Alahmadi, Armiyaw Sebastian Nasamu, Shota Kudo et autres
Plasmodium parasites have repurposed the heme oxygenase scaffold from its canonical heme-degrading function to fulfill an essential and adaptive role in gene expression within the apicoplast organelle.
us, jp
(code pays fourni par la source)
Accès ouvert
2024
peer-review
OpenAlex
Amanda Mixon Blackwell, Yasaman Jami‐Alahmadi, Armiyaw Sebastian Nasamu, Shota Kudo et autres
Malaria parasites have evolved unusual metabolic adaptations that specialize them for growth within heme-rich human erythrocytes. During blood-stage infection, Plasmodium falciparum parasites internalize and digest abundant host hemoglobin within the digestive vacuole. This massive catabolic process generates copious free heme, most of …
us, jp
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Amanda Mixon Blackwell, Yasaman Jami‐Alahmadi, Armiyaw Sebastian Nasamu, Shota Kudo et autres
Abstract Malaria parasites have evolved unusual metabolic adaptations that specialize them for growth within heme-rich human erythrocytes. During blood-stage infection, Plasmodium falciparum parasites internalize and digest abundant host hemoglobin within the digestive vacuole. This massive catabolic process generates copious free heme, most …
us, jp, ru
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Amanda Mixon Blackwell, Yasaman Jami‐Alahmadi, Armiyaw Sebastian Nasamu, Shota Kudo et autres
Malaria parasites have evolved unusual metabolic adaptations that specialize them for growth within heme-rich human erythrocytes. During blood-stage infection, Plasmodium falciparum parasites internalize and digest abundant host hemoglobin within the digestive vacuole. This massive catabolic process generates copious free heme, most of …
us, jp, ru
(code pays fourni par la source)
Accès ouvert
2024
peer-review
OpenAlex
Amanda Mixon Blackwell, Yasaman Jami‐Alahmadi, Armiyaw Sebastian Nasamu, Shota Kudo et autres
Malaria parasites have evolved unusual metabolic adaptations that specialize them for growth within heme-rich human erythrocytes. During blood-stage infection, Plasmodium falciparum parasites internalize and digest abundant host hemoglobin within the digestive vacuole. This massive catabolic process generates copious free heme, most of …
us, jp
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Amanda Mixon Blackwell, Yasaman Jami‐Alahmadi, Armiyaw Sebastian Nasamu, Shota Kudo et autres
Abstract Malaria parasites have evolved unusual metabolic adaptations that specialize them for growth within heme-rich human erythrocytes. During blood-stage infection, Plasmodium falciparum parasites internalize and digest abundant host hemoglobin within the digestive vacuole. This massive catabolic process generates copious free heme, most …
us, jp, ru
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Amanda Mixon Blackwell, Yasaman Jami‐Alahmadi, Armiyaw Sebastian Nasamu, Shota Kudo et autres
ABSTRACT Malaria parasites have evolved unusual metabolic adaptations that specialize them for growth within heme-rich human erythrocytes. During blood-stage infection, Plasmodium falciparum parasites internalize and digest abundant host hemoglobin within the digestive vacuole. This massive catabolic process generates copious free heme, most …
us, jp
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Marie Florence Biabi, Balotin Fogang, Essangui Same Estelle Géraldine, Franklin M. Maloba et autres
Malaria remains a major public health problem worldwide, with eradication efforts thwarted by drug and insecticide resistance and the lack of a broadly effective malaria vaccine. In continuously exposed communities, polyclonal infections are thought to reduce the risk of severe disease and …
Cameroun, us
(code pays fourni par la source)
Accès ouvert
2023
preprint
OpenAlex
Marie Florence Biabi, Balotin Fogang, Estelle Essangui, Franklin M. Maloba et autres
Malaria remains a major public health problem worldwide, with eradication efforts thwarted by drug and insecticide resistance and the lack of a broadly effective malaria vaccine. In continuously exposed communities, polyclonal infections are thought to reduce the risk of severe disease and …
Cameroun, us
(code pays fourni par la source)