Profil bibliographique

A. Nicole

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

3Publications signalées
78Citations signalées
3Affiliations récentes

Les institutions déclarées

Eli Lilly (United States)University of California, San FranciscoUniversity of Minho

Les domaines associés

Glioma Diagnosis and TreatmentRenal cell carcinoma treatmentCancer, Hypoxia, and MetabolismHealth Systems, Economic Evaluations, Quality of LifeBrain Metastases and Treatment

Les publications récentes

Accès ouvert 2011 article OpenAlex

Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma

Nicholas Arthur Butowski, Susan Marina Chang, Kathleen R. Lamborn, M.-Y. Polley et autres

This open-label, single-arm, phase II study combined enzastaurin with temozolomide plus radiation therapy (RT) to treat glioblastoma multiforme (GBM) and gliosarcoma. Adults with newly diagnosed disease and Karnofsky performance status (KPS) ≥ 60 were enrolled. Treatment was started within 5 weeks after …

us, pt (code pays fourni par la source)

77 citations Neuro-Oncology
2010 conference-abstract OpenAlex

Phase II and pharmacogenomics study of enzastaurin plus temozolomide and radiation in patients with GBM.

Nicholas Arthur Butowski, Kathleen R. Lamborn, Mei‐Yin C. Polley, Jennifer Leigh Clarke et autres

2050 Background: ENZ suppresses signaling through PKCβ and the PI3K/AKT pathways. Primary endpoint was overall survival (OS). Secondary endpoints included progression-free survival (PFS). PGx parameters were assessed for correlation to clinical outcomes. Methods: Pts enrolled with newly diagnosed GBM or GS and …

1 citation Journal of Clinical Oncology
Notice OpenAlex

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