Andreza Alice Feitosa Ribeiro

Hematopoietic progenitor cell mobilization, collection, transportation, and infusion of fresh products

Karen de Lima Prata, Andrea Tiemi Kondo, Karine Sampaio Nunes Barroso, Aline Miranda de Souza et autres

Introduction: The quality of the graft is a critical determinant of transplant success. Methods: Literature review and expert discussion. Results: In this review, we highlight the essential aspects of hematopoietic progenitor cell mobilization and collection, including apheresis and bone marrow harvest. We …

br (code pays fourni par la source)

Total marrow irradiation-based, reduced-intensity conditioning regimen for elderly patients undergoing hematopoietic cell transplantation for hematological malignancies

Leonardo Javier Arcuri, Mariana Kerbauy, Lucila Kerbauy, Juliana Rocha et autres

Abstract Background Elderly patients are increasingly being offered allogeneic hematopoietic cell transplantation (HCT), and several strategies have been developed to meet their needs. The objective of the current study was to report the feasibility of a reduced-intensity busulfan/fludarabine conditioning regimen with total …

br, us (code pays fourni par la source)

Current use and outcomes of cellular therapy: Brazilian Summary Slides – 2026

Cinthya Corrêa da Silva, Anderson João Simione, Giancarlo Fatobene, Jayr Schmidt Filho et autres

Objective: To describe CAR-T cell therapy activity and outcomes reported by Brazilian centers participating in the Brazilian Society of Cellular Therapy and Bone Marrow Transplantation (SBTMO)/Center for International Blood and Marrow Transplant Research (CIBMTR) network between January 2020 and December 2025. Methods: …

br, us (code pays fourni par la source)

Current activity trends and outcomes of hematopoietic cell transplantation: A 2026 report from the Brazilian Registry of Hematopoietic Cell Transplantation in collaboration with the CIBMTR & SBTMO

Anderson João Simione, Cinthya Corrêa da Silva, Afonso Celso Vigorito, Antônio Vaz de Macedo et autres

The development of the Brazilian Registry of Hematopoietic Cell Transplantation (Registro Brasileiro de Transplantes de Células Hematopoieticas), in collaboration with the Center for International Blood and Marrow Transplant Research (CIBMTR), continues to provide a comprehensive assessment of hematopoietic cell transplantation (HCT) activity …

br, us, Afrique du Sud (code pays fourni par la source)

Haploidentical Versus HLA-matched Unrelated Donors for Hematopoietic Cell Transplantation in Acute Leukemia: A Multicenter Observational Study in a Developing Country Facilitated by Collaboration Between the CIBMTR and the Brazilian Society of Cellular Therapy and Bone Marrow Transplantation (SBTMO)

Mariana Nassif Kerbauy, Leonardo Javier Arcuri, Vergílio Antônio Rensi Colturato, Mair Pedro de Souza et autres

br, us (code pays fourni par la source)

Impact of Modern Strategies for Graft‐Versus‐Host Disease Prophylaxis on Relapse Risk in Matched‐Sibling or Unrelated Donor Hematopoietic Cell Transplantation: A Systematic Review and Meta‐Analysis of Randomized Trials

Leonardo Javier Arcuri, Victor Natal, André Dias Américo, GF Perini et autres

Regimens combining calcineurin inhibitors with methotrexate or mycophenolate have been the backbone for graft-versus-host disease (GVHD) prophylaxis. Early studies highlighted a delicate dose-response balance. The inclusion criteria comprised randomized clinical trials of patients with hematologic malignancies undergoing sibling- or unrelated-donor transplants, adding …

br, mx, ca (code pays fourni par la source)

Dose Escalation shows no benefit compared to continuing ABVD in Hodgkin's lymphoma patients with an interim PET deauville score of 4

PM Resende, WKP Barros, Barbara Galvão, Carolina Pereira et autres

Abstract Introduction: Interim Fluorodeoxyglucose positron emission tomography (PET) conducted in patients with classic Hodgkin's Lymphoma (cHL) after two cycles of chemotherapy has emerged as a reliable predictor of progression-free survival (PFS) and overall survival (OS), surpassing traditional indicators such as disease stage …

br (code pays fourni par la source)

Impact of high-dose methotrexate in both central nervous system relapse and systemic progression in high-risk DLBCL: A retrospective analysis of a brazilian cohort

PM Resende, WKP Barros, Frederico Honorato, Barbara Galvão et autres

Abstract Background Central nervous system (CNS) relapse in diffuse large B-cell lymphoma (DLBCL) is a rare but devastating event, with dismal prognosis. It is observed particularly in patients with high CNS-International Prognostic Index (CNS-IPI) scores, where 2-year CNS relapse rates can exceed …

br (code pays fourni par la source)

Implementation of a next generation sequencing painel for lymphoid malignancies in Brazil: First report of molecular features in a low-middle income country

PM Resende, Luiz Gustavo Ferreira Cortês, Danielle Ovigli, Newton Centurião et autres

Abstract Background: The understanding of chronic lymphoproliferative disease has advanced significantly with the incorporation of next-generation sequencing (NGS) techniques, allowing for more detailed molecular characterization of the disease. New classifications, such as the ICC and the 5th edition of the WHO Classification, …

br (code pays fourni par la source)

Real-world outcomes of teclistamab in triple-exposed relapsed/refractory multiple myeloma: Brazilian single-center experience

Mariana Nassif Kerbauy, Danielle Ovigli, Newton Centurião, Lucila Nassif Kerbauy et autres

Abstract Background: Teclistamab is a B-cell maturation antigen (BCMA)-targeting bispecific T-cell engager approved for commercialization in Brazil in July 2023 for patients with relapsed/refractory multiple myeloma (RRMM) who have received at least a proteasome inhibitor (PI), an immunomodulatory drug (IMiD), and an …

br (code pays fourni par la source)

More than a bulk: Higher incidence of venous thromboembolism (VTE) in patients with primary mediastinal B-cell lymphoma compared to patients with bulky mediastinal Hodgkin lymphoma

WKP Barros, PM Resende, Luíza Fonseca, Barbara Galvão et autres

Abstract Background: Primary mediastinal B-cell lymphoma (PMBCL) is a rare lymphoma subtype that typically affects young individuals, with a predominance in women (2:1). Although venous thromboembolism (VTE) is a well recognized complication in lymphoma patients, its incidence and associated risk factors in …

br (code pays fourni par la source)

Total marrow irradiation-based, intensified reduced-intensity conditioning regimen for hematopoietic cell transplantation in patients aged 60 years or older: A prospective study

Leonardo Javier Arcuri, Mariana Nassif Kerbauy, Lucila Nassif Kerbauy, Juliana Rocha et autres

Abstract Introduction Although non-myeloablative conditioning regimens are an established option for elderly patients undergoing hematopoietic cell transplantation (HCT), the best reduced-intensity conditioning (RIC) regimen has yet to be determined. Here, we present a single-center analysis of a prospective study using a total …

br, us (code pays fourni par la source)