Accès ouvert
2023
article
OpenAlex
Severin A. Lautenschlager, Mamadou Pathé Barry, Gerhard Rogler, Luc Biedermann et autres
BACKGROUND: Various environmental risk factors have been associated with the pathogenesis of inflammatory bowel disease. In this study we aimed to identify lifestyle factors that affect the onset of Crohn's disease and ulcerative colitis. METHODS: 2294 patients from the Swiss IBD Cohort …
ch
(code pays fourni par la source)
Accès ouvert
2022
erratum
OpenAlex
Eva Goncalves Serra, Tobias Schwerd, Loukas Moutsianas, Athena Cavounidis et autres
Since the publication of this work, Eli M Carrami has changed their name from Mohammad Karaminejadranjbar. This has now been amended in the HTML and PDF versions of the article.
gb, de, pl, ch, ca, it, qa
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Priyatharsan Yoganathan, Jean‐Benoît Rossel, Sebastian Bruno Ulrich Jordi, Yannick Franc et autres
BACKGROUND: Genetic variations within the regulatory region of the gene encoding NOD-like receptor pyrin domain containing 3 (NLRP3) have been associated with Crohn's Disease (CD). NLRP3 is part of the NLRP3-inflammasome that mediates the maturation of IL-1β and IL-18. Carrying the major …
ch
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Philipp Wuggenig, Berna Kaya, Hassan Bachir Melhem, C. Korcan Ayata et autres
Abstract Comprehensive development is critical for gut macrophages being essential for the intestinal immune system. However, the underlying mechanisms of macrophage development in the colon remain elusive. To investigate the function of branched-chain amino acids in the development of gut macrophages, an …
ch
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Eva Goncalves Serra, Tobias Schwerd, Loukas Moutsianas, Athena Cavounidis et autres
Abstract Very-early-onset inflammatory bowel disease (VEO-IBD) is a heterogeneous phenotype associated with a spectrum of rare Mendelian disorders. Here, we perform whole-exome-sequencing and genome-wide genotyping in 145 patients (median age-at-diagnosis of 3.5 years), in whom no Mendelian disorders were clinically suspected. In …
gb, de, pl, ch, ca, it, qa
(code pays fourni par la source)