Jingbo Wang

Evaluation of Artemisia annua-Scutellaria baicalensis Herb Pair Carbon Dots Interfering NLRP3 Inflammatory Pathway For Effective Against H1N1 Viral Pneumonia in Mice Model

Qianyun Zhang, Xinyi Huang, Huimei Kong, Qiongyao Liang et autres

Qianyun Zhang,1,* Xinyi Huang,1,* Huimei Kong,2 Qiongyao Liang,1 Xiaoqing Lv,2 Yuan Ma,1 Jingbo Wang,3 Jing Chen1 1College of Life Science, Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 2College of Life Science, Jinhua University of Vocational Technology, Jinhua, People’s Republic of …

Synergistic effect of HLA evolutionary divergence and post-transplant biomarkers on non-relapse mortality prediction in adult haploidentical hematopoietic stem cell transplantation

Liping Dou, Dan Guan, Yang-Liu Shao, Xiaobo Li et autres

Abstract Background: In hematopoietic stem cell transplantation, post-transplant biomarkers are recognized as reliable prognostic indicators for acute graft-versus-host disease (aGVHD), infections, and organ dysfunction to enable risk stratification for non-relapse mortality (NRM). HLA Evolutionary Divergence (HED), quantifying evolutionary distance between donor and …

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A Pragmatic Monitoring Model for Non-Relapse Mortality Risk Based on Machine Learning in Patients Undergoing Allogeneic Hematopoietic Stem-Cell Transplantation

Yang-Liu Shao, Jingjing Yang, Xiaobo Li, Dan Guan et autres

Background：Prognostic biomarkers play a crucial role in assessing non-relapse mortality (NRM) following allogeneic hematopoietic stem cell transplantation (allo-HSCT).The concentrations of biomarkers fluctuate with the progression of complications and corresponding clinical interventions. However current predictive models are commonly built and applied based on …

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A 1.08pJ/bit DisplayPort RX with Combined AFE Offset Cancellation and Training-Less Link Setup

Yufeng Ge, Zheng Jiang, Yibin Fu, Yaolong Zhang et autres

This paper presents a 0.5~5.4-Gbps, 1.08-pJ/bit receiver (RX) for DisplayPort (DP) V1.2 with an improved rotational frequency detector which permits link setup without training sequence. Adaptive offset compensation realized by a feedback OTA is combined with foreground calibration for the offset of …

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Successful Treatment of Severe Steroid-Resistant Engraftment Syndrome Following Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia with Emapalumab: A Case Report

Zhengqin Tian, Qihang Man, Yixin Yang, Xiaomei Zhang et autres

Engraftment syndrome (ES) is an early complication of hematopoietic stem cell transplantation (HSCT) characterized by fever and additional clinical manifestations including rash, diarrhea, lung infiltrates, weight gain, and neurological symptoms. Steroid-resistant ES following HSCT significantly affects the efficacy of transplantation and may …

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Consensus for antifungal stewardship in China (2024 edition)

Feng Ye, Shaoxi Cai, Bin Cao, Linling Cheng et autres

Background: Invasive fungal disease (IFD) has become a serious threat to human health in China and around the world, with high mortality and morbidity. Currently, the misdiagnosis rate of IFD is extremely high, compounded with the low quality of prescription antifungals and …

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Current situation and development of hematopoietic cell transplantation centers: A nationwide survey in China

Yi Fan, Mimi Xu, Yuqing Tu, Yu Hu et autres

To the Editor: Hematopoietic cell transplantation (HCT) is a vital modality to cure severe hematological disorders.[1] Global or regional summarized data of HCT are annually reported by the Chinese Blood and Marrow Transplantation Registry Group (CBMTRG), European Society for Blood and Marrow …

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Post-transplant cyclophosphamide for GVHD prophylaxis in pediatrics with chronic active Epstein-Barr virus infection after haplo-HSCT

Rongmu Luo, Xiaomei Zhang, Ya Wang, Qihang Man et autres

BACKGROUND: Chronic active Epstein-Barr virus infection (CAEBV) is a rare but life-threatening progressive disease. Human leukocyte antigen (HLA)-haploidentical hematopoietic stem cell transplantation (haplo-HSCT) is the best choice as sometimes HLA-matched donor is not accessible. However, graft-versus-host-disease (GVHD) following transplantation remains a major …

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