Accès ouvert
2025
article
OpenAlex
Obbina Abani, Amr E. Abbas, Fatima H. Abbas, Kaja Abbas et autres
BACKGROUND: Sotrovimab is a neutralising monoclonal antibody targeting the SARS-CoV-2 spike protein. We aimed to evaluate the efficacy and safety of sotrovimab in the RECOVERY trial, an investigator-initiated, individually randomised, controlled, open-label, adaptive platform trial testing treatments for patients admitted to hospital …
Accès ouvert
2022
article
OpenAlex
Obbina Abani, Ali H. Abbas, Fatima H. Abbas, Mustafa A. Abbas et autres
BACKGROUND: Casirivimab and imdevimab are non-competing monoclonal antibodies that bind to two different sites on the receptor binding domain of the SARS-CoV-2 spike glycoprotein, blocking viral entry into host cells. We aimed to evaluate the efficacy and safety of casirivimab and imdevimab …
Accès ouvert
2021
article
OpenAlex
Obbina Abani, Ali H. Abbas, Fatima H. Abbas, Mustafa A. Abbas et autres
BACKGROUND: Aspirin has been proposed as a treatment for COVID-19 on the basis of its anti-thrombotic properties. We aimed to evaluate the efficacy and safety of aspirin in patients admitted to hospital with COVID-19. METHODS: In this randomised, controlled, open-label, platform trial, …
gb, id, np, vn
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Obbina Abani, Ali H. Abbas, Fatima H. Abbas, Mustafa A. Abbas et autres
BACKGROUND: Many patients with COVID-19 have been treated with plasma containing anti-SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent plasma therapy in patients admitted to hospital with COVID-19. METHODS: This randomised, controlled, open-label, platform trial (Randomised Evaluation of …
gb, au
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Eugenia Abaleke, Mustafa A. Abbas, Sadia Abbasi, Alfie Abbott et autres
BACKGROUND: Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatory actions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19. METHODS: In this randomised, controlled, open-label, adaptive platform …
au
(code pays fourni par la source)