Karim Nayernia

Safety and preliminary efficacy of autologous bone marrow-derived mesenchymal stem cell transplantation in hereditary cerebellar ataxia: phase I/IIa clinical trial

A R Saleh Moghaddam, Jalil Tavakol‐Afshari, Najmeh Kaffash Farkhad, Majid Mojarrad et autres

BACKGROUND: Hereditary cerebellar ataxias (HCA) encompass a spectrum of pathological conditions affecting the cerebellum. Currently, there is growing interest in the potential role of mesenchymal stem cells (MSCs) as an investigational therapeutic approach for this condition. Hence, the objective of this single-center, …

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Investigating Germ Cell Transition Genes in Breast Cancer: Exploring the Genesis of Cancer Testis-Associated Markers

Hamid Khodayari, Saeed Khodayari, Mohammad Dashtkoohi, Àmirnader Emami Razavi et autres

Transition is an essential mechanism that drives the development of distinct cellular phenotypes and tumorigenesis. The expression of various types of testis cancer antigens (TCAs) in breast carcinomas suggests a potential transition to male germ cell features within the tumor. This study …

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Overcoming Chemotherapy Resistance in Metastatic Cancer: A Comprehensive Review

Maryam Eslami, Omid Memarsadeghi, Ali Davarpanah, Afshin Arti et autres

The management of metastatic cancer is complicated by chemotherapy resistance. This manuscript provides a comprehensive academic review of strategies to overcome chemotherapy resistance in metastatic cancer. The manuscript presents background information on chemotherapy resistance in metastatic cancer cells, highlighting its clinical significance …

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Single-Cell Transcriptomics for Unlocking Personalized Cancer Immunotherapy: Toward Targeting the Origin of Tumor Development Immunogenicity

Saeed Khodayari, Hamid Khodayari, Elnaz Saeedi, Habibollah Mahmoodzadeh et autres

Cancer immunotherapy is a promising approach for treating malignancies through the activation of anti-tumor immunity. However, the effectiveness and safety of immunotherapy can be limited by tumor complexity and heterogeneity, caused by the diverse molecular and cellular features of tumors and their …

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Molecular Mechanisms for Targeting Metastatic Cancer Cells and to Overcome or Prevent Chemotherapy Resistance

Maryam Eslami, Ali Davarpanah, Amirhossein Rismanbaf, Farzad Taghizadeh‐Hesary et autres

Cancer is a devastating disease, causing tremendous morbidity and mortality each year. Cancer can be considered as a genetic disease in the sense that instabilities in protooncogenes and tumor suppressor genes are among the hallmarks of cancer progression and metastasis. However, a …

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Supplementary Table 2 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Jae Ho Lee, Cornelia Jung, Parisa Javadian-Elyaderani, Stefan Schweyer et autres

Supplementary Table 2 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Supplementary Figure Legends 1-7 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Jae Ho Lee, Cornelia Jung, Parisa Javadian-Elyaderani, Stefan Schweyer et autres

Supplementary Figure Legends 1-7 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Supplementary Figures 1-7 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Jae Ho Lee, Cornelia Jung, Parisa Javadian-Elyaderani, Stefan Schweyer et autres

Supplementary Figures 1-7 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Supplementary Table 1 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Jae Ho Lee, Cornelia Jung, Parisa Javadian-Elyaderani, Stefan Schweyer et autres

Supplementary Table 1 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Supplementary Table 2 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Jae Ho Lee, Cornelia Jung, Parisa Javadian-Elyaderani, Stefan Schweyer et autres

Supplementary Table 2 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Supplementary Figure Legends 1-7 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Jae Ho Lee, Cornelia Jung, Parisa Javadian-Elyaderani, Stefan Schweyer et autres

Supplementary Figure Legends 1-7 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Supplementary Table 1 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2

Jae Ho Lee, Cornelia Jung, Parisa Javadian-Elyaderani, Stefan Schweyer et autres

Supplementary Table 1 from Pathways of Proliferation and Antiapoptosis Driven in Breast Cancer Stem Cells by Stem Cell Protein Piwil2