Profil bibliographique

Rosario Concepcion Riesco

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

2Publications signalées
2Citations signalées
0Affiliations récentes

Les domaines associés

Synthesis and biological activityCancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancerAdvanced Breast Cancer TherapiesCancer Mechanisms and Therapy

Les publications récentes

2016 conference-abstract OpenAlex

Abstract 4337: Novel potent and selective orally available CDK8/19 kinase inhibitors

Carmen Blanco‐Aparicio, Oliver Renner, Elena Gómez‐Casero, Maria Isabel Albarran et autres

Abstract CDK8 and its paralog CDK19 are cyclin-dependent kinases and together with CDK7 and CDK9 belongs to the group of C-terminal domain (CTD) kinases that phosphorylate the CTD of RNA polymerase II, thus regulating transcription. CDK8 together with its partner Cyclin C, …

0 citations Cancer Research
2013 conference-abstract OpenAlex

Abstract A275: Co-targeting PIM and PI3K/mTOR pathways with a single molecule: Novel orally available combined PIM/PI3K and PIM/PI3K/mTOR kinase inhibitors.

Carmen Blanco‐Aparicio, Oliver Renner, Elena Gómez‐Casero, Antonio Cebriá et autres

Abstract The PI3K/AKT pathway is commonly activated in human cancer. Multiple small-molecule inhibitors have been developed to target PI3K/mTOR or AKT kinases, but the efficacy of these drugs is compromised by the stimulation of compensatory signaling pathways. The redundancy of oncogenic signaling …

es (code pays fourni par la source)

2 citations Molecular Cancer Therapeutics
Notice OpenAlex

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