Itziar Salaverria

HIGH RESOLUTION ARCHITECTURE OF IRF4 REARRANGEMENTS IN CHILDREN AND ADULTS

Ariadna Colmenero, Leonie Frauenfeld, Sara Mato, Ferran Nadeu et autres

MUTATION SITES INFLUENCE PROGNOSTIC SIGNIFICANCE OF TP53 MUTATIONS IN PEDIATRIC B-CELL NON-HODGKIN LYMPHOMA

Marcel te Vrugt, Amelie Alfert, Lara Mussolin, Mara Andrés et autres

Abstract 2502: Unravelling the heterogenous molecular landscape of pediatric post-transplant lymphoproliferative disorders

Julia Salmerón, Natalia Castrejón de Anta, Pilar Guerra‐García, Joan E. Ramis-Zaldivar et autres

Abstract The genetic landscape of post-transplant lymphoproliferative disorders (PTLD) in pediatric population has not been fully elucidated. This absence of information raises the question whether therapeutic strategies should be the same as for their counterparts in immunocompetent (IC) patients. The aim of …

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Diverse mutations and structural variations contribute to Notch signaling deregulation in paediatric T-cell lymphoblastic lymphoma

Julia Salmerón‐Villalobos, Juan Enric Ramis‐Zaldivar, Olga Balagué, Jaime Verdú‐Amorós et autres

Background T-cell lymphoblastic lymphoma (T-LBL) is an aggressive neoplasm closely related to T-cell acute lymphoblastic leukaemia (T-ALL). Despite their similarities, and contrary to T-ALL, studies on pediatric T-LBL are scarce and, therefore, its molecular landscape has not been fully elucidated yet. Procedure …

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