Accès ouvert
2021
article
OpenAlex
James B. Regan, James P. Flynn, Alexandra Rosenthal, Hannah T. Jordan et autres
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) kinetics remain understudied, including the impact of remdesivir. In hospitalized individuals, peak sputum viral load occurred in week 2 of symptoms, whereas viremia peaked within 1 week of symptom-onset, suggesting early systemic seeding of SARS-CoV-2. …
us
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Accès ouvert
2020
article
OpenAlex
Jesse M. Fajnzylber, James B. Regan, Kendyll Coxen, Heather Corry et autres
The relationship between SARS-CoV-2 viral load and risk of disease progression remains largely undefined in coronavirus disease 2019 (COVID-19). Here, we quantify SARS-CoV-2 viral load from participants with a diverse range of COVID-19 disease severity, including those requiring hospitalization, outpatients with mild …
us
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Ellen L. Shrock, Eric Fujimura, Tomasz Kula, Richard T. Timms et autres
Understanding humoral responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for improving diagnostics, therapeutics, and vaccines. Deep serological profiling of 232 coronavirus disease 2019 (COVID-19) patients and 190 pre-COVID-19 era controls using VirScan revealed more than 800 epitopes in …
us, Afrique du Sud
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