Accès ouvert
2024
article
OpenAlex
Jay Bowen, Jonathan C. Silverstein, AURORA US Network, Melina E Sanders et autres
The AURORA US Metastasis Project was established with the goal to identify molecular features associated with metastasis. We assayed 55 females with metastatic breast cancer (51 primary cancers and 102 metastases) by RNA sequencing, tumor/germline DNA exome and low-pass whole-genome sequencing and …
us
(code pays fourni par la source)
Accès ouvert
2021
review
OpenAlex
R. Schiff, V. Guarneri, C.M. Perou, P.F. Conte et autres
Background: HER2-positive (HER2+) breast cancer (BC) comprises all the four PAM50 molecular subtypes. Among these, the HER2-Enriched (HER2-E) appear to be associated with higher pathological complete response (pCR) rates following anti-HER2-based regimens. Here, we present a meta-analysis to validate the association of …
us
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
J. Cortés, Enrico Tagliafico, V. Guarneri, G. Griguolo et autres
Background: In early-stage HER2-positive breast cancer, escalation or de-escalation of systemic therapy is a controversial topic. As an aid to treatment decisions, we aimed to develop a prognostic assay that integrates multiple data types for predicting survival outcome in patients with newly …
us
(code pays fourni par la source)