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Profil bibliographique

Martin Berghoff

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

88Publications signalées
1920Citations signalées
0Affiliations récentes

Les domaines associés

Multiple Sclerosis Research StudiesFibroblast Growth Factor ResearchHereditary Neurological DisordersKruppel-like factors researchPeripheral Neuropathies and Disorders

Les publications récentes

Accès ouvert 2026 article OpenAlex

Immune cell profiling reveals expanded stem cell–like memory T cells in anti-GAD65-associated neurological syndromes

Sumanta Barman, Saskia Räuber, Katharina Eisenhut, Daniela Esser et autres

The immunopathogenesis of autoimmune neurological syndromes (AINS) with antibodies against the 65 kDa isoform of glutamic acid decarboxylase (anti-GAD65 AINS) remains poorly understood. To elucidate underlying disease mechanisms and identify relevant cell populations, we performed single-cell RNA and immune repertoire sequencing of …

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2 citations Proceedings of the National Academy of Sciences
Accès ouvert 2026 article OpenAlex

Reduced Hospital Incidence of Autoimmune Encephalitis During the COVID-19 Pandemic

Jonathan Wickel, Ha‐Yeun Chung, Franz Felix Konen, Rosa Rössling et autres

OBJECTIVES: The aim of this study was to analyze changes in hospital incidence cases and disease severity of autoantibody-associated autoimmune encephalitis (AE) during the COVID-19 pandemic compared with the prepandemic period. METHODS: A retrospective multicenter study analyzed data from 24 centers within …

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0 citations Neurology Neuroimmunology & Neuroinflammation
Accès ouvert 2025 article OpenAlex

Risk of Epilepsy and Factors Associated With Time to Seizure Remission in Anti-LGI1 Encephalitis

Tobias R. Baumgartner, Moritz Freyberg, Lucia Campetella, Yvette S. Crijnen et autres

BACKGROUND AND OBJECTIVES: Autoimmune encephalitis (AIE) with anti-leucine-rich glioma-inactivated 1 (LGI1) antibodies typically manifests with subacute cognitive deficits, seizures, and psychiatric symptoms, mostly in older adults. Immunotherapy (IT) leads to the cessation of seizures in most patients, yet some develop AIE-associated epilepsy …

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3 citations Neurology Neuroimmunology & Neuroinflammation
Accès ouvert 2025 article OpenAlex

Characterization of growth differentiation factor 15 (GDF15) as a neurotropic adipokine permeable to the brain

Andreas Alexander Schmid, Emily Wilfurth, Alexandra Höpfinger, Edita Islami et autres

Abstract GDF15 (growth/differentiation factor-15) belongs to the superfamily of transforming growth factor-beta. Little is known about adipocytic regulation of GDF15, its concentrations in serum and cerebrospinal fluid (CSF), its permeability to the brain, and its correlation with neurological diseases. This knowledge is …

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5 citations Scientific Reports
Accès ouvert 2025 article OpenAlex

Early Treatment With Intravenous Immunoglobulins and Outcomes of Patients With Anti-IgLON5 Disease

Thomas Grüter, Carles Gaig, Yvette S. Crijnen, Maarten J. Titulaer et autres

Importance: Anti-IgLON5 disease is an autoimmune encephalopathy that often leads to severe disability or death. The efficacy of immunotherapy remains unknown. Objective: To investigate whether early immunotherapy is associated with disability and death in anti-IgLON5 disease. Design, Setting, and Participants: This retrospective, …

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12 citations JAMA Neurology
Accès ouvert 2025 article OpenAlex

Serum Alpha-Linolenic Acid and Long-Term Multiple Sclerosis Activity and Progression

Marianna Cortese, Xiaojing Peng, Gilles Edan, Mark Steven Freedman et autres

BACKGROUND AND OBJECTIVES: Higher dietary intake of alpha-linolenic acid (ALA), a plant-derived omega-3 polyunsaturated fatty acid (PUFA), was associated with a lower risk of multiple sclerosis (MS) in a prospective cohort study and lower risk of new lesions, relapses, and disability progression …

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4 citations Neurology
Accès ouvert 2025 article OpenAlex

Comorbidities and Their Influence on Outcomes and Infectious Complications in Autoimmune Encephalitis

Amelie Bohn, Klemens Angstwurm, Christian G. Bien, Kathrin Doppler et autres

BACKGROUND AND OBJECTIVES: Comorbidities greatly influence the course of many diseases. However, systematic data on comorbidities in patients with autoimmune encephalitis (AE) are scarce. We aimed to characterize comorbidities in patients with common AE variants and assess their influence on outcome and …

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0 citations Neurology Neuroimmunology & Neuroinflammation
Accès ouvert 2025 article OpenAlex

Anti-inflammatory and remyelinating effects of fexagratinib in experimental multiple sclerosis

Fynn Gurski, Kian Shirvanchi, Vinothkumar Rajendran, R. Rajendran et autres

Background and Purpose: FGF, VEGFR-2 and CSF1R signalling pathways play a key role in the pathogenesis of multiple sclerosis (MS). Selective inhibition of FGFR by infigratinib in MOG35-55-induced experimental autoimmune encephalomyelitis (EAE) prevented severe first clinical episodes by 40%; inflammation and neurodegeneration …

0 citations Universitätsbibliothek Gießen
Accès ouvert 2024 article OpenAlex

A Cross-Sectional Study: Systematic Quantification of Chemerin in Human Cerebrospinal Fluid

Alexandra Höpfinger, Andreas Alexander Schmid, Thomas Karrasch, Andreas Schäffler et autres

Background: Dysregulation of adipokines is considered a key mechanism of chronic inflammation in metabolic syndrome. Some adipokines affect food intake by crossing the blood/brain barrier. The adipokine chemerin is associated with metabolic syndrome, cardiovascular diseases and immune response. Little is known about …

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5 citations Biomedicines
Accès ouvert 2024 article OpenAlex

Anti‐inflammatory and remyelinating effects of fexagratinib in experimental multiple sclerosis

Fynn Gurski, Kian Shirvanchi, Vinothkumar Rajendran, R. Rajendran et autres

Abstract Background and Purpose FGF, VEGFR‐2 and CSF1R signalling pathways play a key role in the pathogenesis of multiple sclerosis (MS). Selective inhibition of FGFR by infigratinib in MOG 35‐55 ‐induced experimental autoimmune encephalomyelitis (EAE) prevented severe first clinical episodes by 40%; …

de (code pays fourni par la source)

5 citations British Journal of Pharmacology
2024 preprint OpenAlex

Anti-inflammatory and remyelinating effects of AZD4547 in experimental multiple sclerosis

Fynn Gurski, Kian Shirvanchi, Vinothkumar Rajendran, R. Rajendran et autres

Background and Purpose: Fibroblast Growth Factor (FGF), VEGFR2, and CSF1R signalling pathways play a key role in the pathogenesis of multiple sclerosis (MS). Selective inhibition of FGFR by infigratinib in MOG35-55-induced EAE prevented severe first clinical episodes by 40%; inflammation and neurodegeneration …

de (code pays fourni par la source)

0 citations

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