RNA Interference With Zilebesiran for Mild to Moderate Hypertension
George L. Bakris, Manish Saxena, Anil Gupta, Fadi Chalhoub et autres
Importance: Angiotensinogen is the most upstream precursor of the renin-angiotensin-aldosterone system, a key pathway in blood pressure (BP) regulation. Zilebesiran, an investigational RNA interference therapeutic, targets hepatic angiotensinogen synthesis. Objective: To evaluate antihypertensive efficacy and safety of different zilebesiran dosing regimens. Design, …
us, gb (code pays fourni par la source)