BMAL1 loss in oligodendroglia contributes to abnormal myelination and sleep
Daniela Rojo, Louisa Dal Cengio, Anna Badner, Samuel Kim et autres
Myelination depends on the maintenance of oligodendrocytes that arise from oligodendrocyte precursor cells (OPCs). We show that OPC-specific proliferation, morphology, and BMAL1 are time-of-day dependent. Knockout of Bmal1 in mouse OPCs during development disrupts the expression of genes associated with circadian rhythms, …
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