Elisa Sibilla

Discriminating behavioral variant frontotemporal dementia from Alzheimer’s disease via the Frontal Assessment Battery

Edoardo Nicolò Aiello, Elisa Canu, Veronica Castelnovo, Francesca Frisco et autres

it (code pays fourni par la source)

Baseline blink reflex R2 changes correlate with affective and interoceptive domains in functional movement disorders

Claudia Vinciguerra, Marialuisa Gandolfi, Angela Sandri, Michela Russo et autres

it, cz (code pays fourni par la source)

305 Neural Correlates of Central Pain in Trigeminal Neuralgia: A Functional MRI Analysis

Luigi Albano, Silvia Basaia, Filippo Valtorta, Edoardo Pompeo et autres

INTRODUCTION: Growing evidence supports the role of central nervous system in the modulation of pain in trigeminal neuralgia (TN) patients. METHODS: Twelve TN patients underwent clinical assessment and brain MRI protocol including observation task fMRI on a 3 Tesla scanner before and …

Real-world implementation of lecanemab and donanemab in an Italian memory center: a 1-year experience

Federica Agosta, Giordano Cecchetti, Edoardo G. Spinelli, Alma Ghirelli et autres

BACKGROUND: Anti-amyloid monoclonal antibodies are entering clinical practice for early symptomatic Alzheimer’s disease (AD), but European real-world data on feasibility, safety, and biomarker monitoring remain limited. We report the first year of implementation of lecanemab and donanemab in an Italian tertiary memory …

it (code pays fourni par la source)

Resting-State EEG captures functional network correlates of plasma p-Tau-217 in Alzheimer’s disease

Giordano Cecchetti, Jacopo Lanzone, Luca Zanchi, Giulia Rugarli et autres

BACKGROUND: Scalable biomarkers are needed for early Alzheimer's disease (AD) detection. Plasma p-tau217 reflects AD pathology, while resting-state EEG captures functional brain alterations. Their relationship remains unclear. METHODS: We enrolled 128 patients with subjective cognitive decline (SCD), mild cognitive impairment due to …

it (code pays fourni par la source)

Distinctive Progression Patterns of Brain Structural Damage Aid Classification of Frontotemporal Dementia Variants

Edoardo Gioele Spinelli, Francesca Orlandi, Silvia Basaia, Francesco Costa et autres

BACKGROUND: Frontotemporal dementia (FTD) encompasses diverse clinical phenotypes, primarily characterized by behavioral and/or language dysfunction. A newly characterized variant, semantic behavioral variant FTD (sbvFTD), exhibits predominant right temporal atrophy with features bridging behavioral variant FTD (bvFTD) and semantic variant primary progressive aphasia …

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Handwriting, touchscreen dexterity and bradykinesia measures in Parkinson’s disease: a feature selection study

Andrea Gardoni, Elisabetta Sarasso, Silvia Basaia, Davide Corbetta et autres

it (code pays fourni par la source)

Distinctive Brain Atrophy Progression Patterns Aid Classification of Frontotemporal Dementia Variants (P4-3.011)

Edoardo Gioele Spinelli, Francesca Orlandi, Silvia Basaia, Francesco Costa et autres

To describe longitudinal structural MRI correlates of clinically overlapping frontotemporal dementia (FTD) variants, describing their patterns of cortical and subcortical atrophy and assessing their utility for differential diagnosis and prognosis.

it, fr, us (code pays fourni par la source)

Frontotemporal dementia characterization using neurite orientation dispersion and density imaging

Stefano Pisano, Silvia Basaia, Federica Agosta, Elisa Canu et autres

Microstructural alterations in brain tissue play a crucial role in the pathophysiology of frontotemporal dementia (FTD). This study assessed brain white matter (WM) and grey-matter (GM) microstructure in FTD variants using neurite orientation dispersion and density imaging (NODDI) diffusion MRI model and …

it, Afrique du Sud (code pays fourni par la source)

A common marker of affect recognition dysfunction in the FTD spectrum of disorders

Elisa Canu, Veronica Castelnovo, Edoardo Nicolò Aiello, Giulia De Luca et autres

BACKGROUND: Poor affect recognition is an early sign of frontotemporal dementia (FTD). Here, we applied the abbreviated version of the Comprehensive Affect Testing System (CATS-A) battery to Italian FTD cases and healthy controls (HC) to provide cut-offs of emotional dysfunction in the …

it, us (code pays fourni par la source)

Modelling pathological spread through the structural connectome in the frontotemporal dementia clinical spectrum

Federica Agosta, Silvia Basaia, Edoardo Gioele Spinelli, Federica Facente et autres

The ability to predict the spreading of pathology in patients with frontotemporal dementia (FTD) is crucial for early diagnosis and targeted interventions. In this study, we examined the relationship between network vulnerability and longitudinal progression of atrophy in FTD patients, using the …

it, Afrique du Sud, fr, us (code pays fourni par la source)

A window into the mind-brain-body interplay: Development of diagnostic, prognostic biomarkers, and rehabilitation strategies in functional motor disorders

Marialuisa Gandolfi, Angela Sandri, Sara Mariotto, Stefano Tamburin et autres

BACKGROUND AND AIMS: Functional motor disorders (FMD) present a prevalent, yet misunderstood spectrum of neurological conditions characterized by abnormal movements (i.e., functional limb weakness, tremor, dystonia, gait impairments), leading to substantial disability and diminished quality of life. Despite their high prevalence, FMD …

it (code pays fourni par la source)