Paolo Visca

EP.03.02 An Integrating Multiomic Approach to Chart the Tumor Immune Microenvironment Associated to Immunotherapy Response in Non-Small Cell Lung Cancer

F.T. Gallina, Nicla Porciello, Giovanni Frisullo, Luigi D’Ambrosio et autres

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Structure–function relationship of the Pseudomonas aeruginosa AsmA ‐like proteins YhdP and YdbH involved in outer membrane biogenesis

Davide Sposato, Camilla Pederzoli, M Bufano, Pietro Sciò et autres

The outer membrane (OM) of Gram-negative bacteria is an asymmetric bilayer composed of glycerophospholipids (GPLs) in the inner leaflet and lipopolysaccharide in the outer leaflet, which is critical for viability and antibiotic resistance. While the mechanisms for lipopolysaccharide and OM protein transport …

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Short term outcomes of robotic surgery after neoadjuvant treatment for locally advanced NSCLC: a comparison with the open approach

Filippo Tommaso Gallina, Riccardo Tajè, Daniele Forcella, Gabriele Alessandrini et autres

Introduction: Despite thoracotomy remaining the gold standard in the treatment of locally advanced NSCLC after induction treatment, robotic surgery may improve perioperative outcomes. The object of this study is to compare robotic surgery with thoracotomy for the treatment of NSCLC after neoadjuvant …

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Molecular characterization of early-stage lung adenocarcinoma presenting as subsolid nodules in a real-life European cohort

Riccardo Tajè, Filippo Tommaso Gallina, M Caterino, Daniele Forcella et autres

OBJECTIVES: Subsolid nodules emerged as frequent radiological variants of lung adenocarcinoma. Radiological features including solid-component prevalence and larger tumour dimensions prompt tumoral invasiveness guiding prognosis and management. Thus, we aimed to clarify the molecular grounds that dictate these radiological appearances and clinical …

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BRAF mutation and neoadjuvant chemo-immunotherapy, is it worthwhile?

Filippo Tommaso Gallina, Fabiana Letizia Cecere, Serenella Bergomi, Simonetta Buglioni et autres

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219P: Real-world outcomes of lung resections after neoadjuvant chemo-immunotherapy for resectable NSCLC: A single-center experience

Filippo Tommaso Gallina, R. Tajè, Flavia Fusco, Fabiana Letizia Cecere et autres

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402P: Tumor suppressor genes (TSG) in NSCLC with gene fusions

Lorenza Landi, M. Giammaruco, F. Bartoccini, A. Torchia et autres

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DESTINY of Immunotherapy in Patients With HER2 Mutant Lung Cancer: Case Report

Lorenza Landi, Francesca Fusco, Enrico Melis, Simonetta Buglioni et autres

Immunotherapy has significantly transformed the landscape of non–oncogene-driven NSCLC. Multiple trials have reported that immunotherapy, either alone or in combination with chemotherapy, can induce pathologic complete responses—essentially tumor eradication—in non–oncogene-driven patients, at least in resectable stages. In contrast, tumors with specific molecular …

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Impact and Reproducibility of In-House Targeted Next-Generation Sequencing Biomarker Testing in Non–Small-Cell Lung Cancer

Ida Rapa, Francesca Bertola, Gaia Roversi, Davide Seminati et autres

Next-generation sequencing (NGS) allows the detection of multiple genetic targets in different tumor types. This study aimed to confirm the benefits of implementing in-house NGS testing for non–small-cell lung cancer (NSCLC) samples in molecular pathology laboratories. A multi-institutional study was conducted to …

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Kirsten Rat Sarcoma Virus Mutations Effect On Tumor Doubling Time And Prognosis Of Solid Dominant Stage I Lung Adenocarcinoma

Riccardo Tajè, Vincenzo Ambrogi, Federico Tacconi, Filippo Tommaso Gallina et autres

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Identifying Transcriptomic Biomarkers for Predicting Aggressive Metastatic Phenotypes in Melanoma

Marta Betti, Italia Falcone, Cristina Accetta, Elisa Melucci et autres

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Phenotype switching regulates drug-resistance in metastatic melanoma

Cristina Accetta, Italia Falcone, Marta Betti, Brindusa Ana Maria Arteni et autres

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