Esther Nyimbili

NTHi killing activity is reduced in COPD patients and is associated with a differential microbiome

Vancheswaran Gopalakrishnan, Ben Sparklin, Jung Hwan Kim, Jérôme Bouquet et autres

Chronic obstructive pulmonary disease (COPD) is a chronic lung disease characterized by airway obstruction and inflammation. Non-typeable Haemophilus influenzae (NTHi) lung infections are common in COPD, promoting frequent exacerbations and accelerated lung function decline. The relationship with immune responses and NTHi are …

us, se, gb, kr (code pays fourni par la source)

Clinical impact of a routine, molecular, point-of-care, test-and-treat strategy for influenza in adults admitted to hospital (FluPOC): a multicentre, open-label, randomised controlled trial

Tristan Clark, Kate Beard, Nathan J. Brendish, Ahalya Malachira et autres

gb (code pays fourni par la source)

120. Impact of a Molecular Point-of-care ‘test and Treat’ Strategy for Influenza in Hospitalised adults: A Multi-centre, Randomised Controlled Trial (FluPOC)

Tristan Clark, Kate Beard, Nathan J. Brendish, Ahalya Malachira et autres

Abstract Background The diagnosis of Influenza in hospitalised patients is delayed due to long turnaround times of laboratory testing, leading to inappropriate and late antiviral and isolation facility use. Molecular point-of-care test (mPOCT) are highly accurate, easy to use and generate results …

gb (code pays fourni par la source)

Does nasal rinsing reduce the need for repeat nasal brushing biopsies in a primary ciliary dyskinesia (PCD) diagnostic service? A pilot study.

Amanda Harris, Victoria Keenan, Amanda Friend, Hannah Wilkins et autres

Background: PCD is a rare genetic condition. Nasal brushing biopsies are used to sample ciliated epithelium for PCD diagnostic testing. High-speed video microscpy (HSVM) analysis of ciliary function can be difficult when excess mucus impedes cilia, increasing the likelihood or repeat testing …

gb (code pays fourni par la source)

Routine molecular point-of-care testing for respiratory viruses in adults presenting to hospital with acute respiratory illness (ResPOC): a pragmatic, open-label, randomised controlled trial

Nathan J. Brendish, Ahalya Malachira, Lawrence Armstrong, Rebecca Houghton et autres

gb (code pays fourni par la source)