Dieudonné Mpoyi Muamba

An Open-Label Study of the Effectiveness and Safety of Fexinidazole for Gambiense Human African Trypanosomiasis, Including an Exploration of Adherence in Outpatients

Victor Kande Betu Ku Mesu, Christelle Perdrieu, Caroline Menétrey, Médard Ilunga Wa Kyhi et autres

République démocratique du Congo, ch, Burkina Faso, Nigéria, Ouganda, Guinée, jp, ae, au, br, cn, fr (code pays fourni par la source)

Trypanosome spliced leader RNA for diagnosis of acoziborole treatment outcome in gambiense human African trypanosomiasis: A longitudinal follow-up study

Ipos Ngay Lukusa, Nick Van Reet, Dieudonné Mumba Ngoyi, Erick Mwamba Miaka et autres

BACKGROUND: Detection of spliced leader (SL)-RNA allows sensitive diagnosis of gambiense human African trypanosomiasis (HAT). We investigated its diagnostic performance for treatment outcome assessment. METHODS: Blood and cerebrospinal fluid (CSF) from a consecutive series of 97 HAT patients, originating from the Democratic …

République démocratique du Congo, be, ch, fr (code pays fourni par la source)

Trypanosome SL-RNA detection in blood and cerebrospinal fluid to demonstrate active gambiense human African trypanosomiasis infection

Ipos Ngay Lukusa, Nick Van Reet, Dieudonné Mumba Ngoyi, Erick Mwamba Miaka et autres

BACKGROUND: Spliced Leader (SL) trypanosome RNA is detectable only in the presence of live trypanosomes, is abundant and the Trypanozoon subgenus has a unique sequence. As previously shown in blood from Guinean human African trypanosomiasis (HAT) patients, SL-RNA is an accurate target …

République démocratique du Congo, be, ch, fr (code pays fourni par la source)