LAB-ANGIOGENESIS AND INVASION
M. A. Proescholdt, Marsha J. Merrill, Eva-Maria Stoerr, A. Lohmeier et autres
OBJECTIVE: Glioblastoma multiforme is the most frequent primary brain tumor in adults. The major obstacle for successful treatment is the invasive growth pattern. Metabolically, glioblastomas are highly glycolytic, leading to increased levels of lactic acid production. The carbonic anhydrase IX (CAIX) moderates …
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