Abstract 2759: Chemoproteomic profiling of the oncometabolite fumarate
Sarah E. Bergholtz, Chloe A. Briney, Rhushikesh A. Kulkarni, David Wei et autres
Dysregulated metabolism is a feature of many diseases, including cancer. In addition to providing energy and building blocks to growing cells, altered metabolism can assist in tumor growth by producing “oncometabolites”. For example, in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) inactivating …
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