IL-7-dependent and -independent lineages of IL-7R-dependent human T cells
Carlos A. Arango-Franco, Masato Ogishi, Sheila Unger, Ottavia M. Delmonte et autres
Infants with biallelic IL7R loss-of-function variants have severe combined immune deficiency (SCID) characterized by the absence of autologous T lymphocytes, but normal counts of circulating B and NK cells (T–B+NK+ SCID). We report 6 adults (aged 22 to 59 years) from 4 …