Amos Bennin

Microbiology testing capacity and antimicrobial drug resistance in surgical-site infections: a post-hoc, prospective, secondary analysis of the FALCON randomised trial in seven low-income and middle-income countries

Aaron Oladipo Aboderin, Solomon Amfoabegyi, A. T. O. Awopeju, Michael Bahrami‐Hessari et autres

BACKGROUND: Surgical-site infection (SSI) is one of the most common health-care-associated infections, substantially contributing to antibiotic use. Targeted antibiotic prophylaxis to prevent SSIs and effective treatment are crucial to controlling antimicrobial resistance (AMR). This study aimed to describe the testing capacity and …

Accuracy of the Wound Healing Questionnaire in the diagnosis of surgical-site infection after abdominal surgery in low- and middle-income countries

James C Glasbey, Adesoji Oludotun Ademuyiwa, Alisha Bhatt, Bruce McClure Biccard et autres

INTRODUCTION: Telemedicine is being adopted for postoperative surveillance but requires evaluation for efficacy. This study tested a telephone Wound Healing Questionnaire (WHQ) to diagnose surgical site infection (SSI) after abdominal surgery in low- and middle-income countries. METHOD: A multi-centre, international, prospective study …

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Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a model-based cost-effectiveness analysis of a pragmatic, cluster-randomised trial in seven low-income and middle-income countries

Mwayi Kachapila, Raymond Oppong, Adesoji Oludotun Ademuyiwa, Aneel A Bhangu et autres

BACKGROUND: Surgical site infection (SSI) is a major burden on patients and health systems. This study assessed the cost-effectiveness of routine change of sterile gloves and instruments before abdominal wall closure to prevent SSI. METHODS: A decision-analytic model was built to estimate …

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The importance of post-discharge surgical site infection surveillance: an exploration of surrogate outcome validity in a global randomised controlled trial (FALCON)

James C Glasbey, Bryar Kadir, Adesoji Oludotun Ademuyiwa, Adewale Adisa et autres

Surgical site infection (SSI) is the most common complication of abdominal surgery worldwide and was recognised as the highest priority research area in surgery in a global consensus process.1 The accepted gold standard for diagnosis of SSI is in-person evaluation according to …

Strategies to minimise and monitor biases and imbalances by arm in surgical cluster randomised trials: evidence from ChEETAh, a trial in seven low- and middle-income countries

Didier Ahogni, Aristide Ahounou, K. Alassan Boukari, Oswald Gbéhadé et autres

BACKGROUND: Cluster randomised controlled trials (cRCT) present challenges regarding risks of bias and chance imbalances by arm. This paper reports strategies to minimise and monitor biases and imbalances in the ChEETAh cRCT. METHODS: ChEETAh was an international cRCT (hospitals as clusters) evaluating …

Adaptation of the Wound Healing Questionnaire universal-reporter outcome measure for use in global surgery trials (TALON-1 study): mixed-methods study and Rasch analysis

James C Glasbey, Alisha Bhatt, Bruce McClure Biccard, Jane M. Blazeby et autres

BACKGROUND: The Bluebelle Wound Healing Questionnaire (WHQ) is a universal-reporter outcome measure developed in the UK for remote detection of surgical-site infection after abdominal surgery. This study aimed to explore cross-cultural equivalence, acceptability, and content validity of the WHQ for use across …

gb (code pays fourni par la source)

Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a pragmatic, cluster-randomised trial in seven low-income and middle-income countries

Aaron B Andoh, Abantanga Atindaana Francis, Abdulhafiz Abubakar Abdulkarim, AbdulHafiz Oladapo Adesunkanmi et autres

BACKGROUND: Surgical site infection (SSI) remains the most common complication of surgery around the world. WHO does not make recommendations for changing gloves and instruments before wound closure owing to a lack of evidence. This study aimed to test whether a routine …

Reducing surgical site infections in low-income and middle-income countries (FALCON): a pragmatic, multicentre, stratified, randomised controlled trial

Adesoji Oludotun Ademuyiwa, Emmy Runigamugabo, Pierre Sodonougbo, Hulrich Aouagbe Behanzin et autres

BACKGROUND: Surgical site infection (SSI) is the most common postoperative complication worldwide. WHO guidelines to prevent SSI recommend alcoholic chlorhexidine skin preparation and fascial closure using triclosan-coated sutures, but called for assessment of both interventions in low-resource settings. This study aimed to …

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