Phase 1a Evaluation of LP-184 in Recurrent Glioblastoma: Safety, Pharmacokinetics, and Translational Optimization of CNS Exposure
Karisa C. Schreck, Bachchu Lal, Jianli Zhou, Hernando Lopez Bertoni et autres
0 citationsmedRxiv
Kishor Bhatia
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355Publications signalées
8917Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
Lymphoma Diagnosis and TreatmentViral-associated cancers and disordersATP Synthase and ATPases ResearchPARP inhibition in cancer therapyDNA Repair Mechanisms
Publications récentes
Abstract CT116: Data-driven characterization of platelet count and alanine aminotransferase dynamics in the first-in-human LP-184 dose escalation trial
Jianli Zhou, Daruka Mahadevan, Jay Parekh, Marc Chamberlain et autres
0 citationsCancer Research
Identification of sensitive and resistant genes to compound LP-184 by Genome-wide CRISPR KO screen
The University of Texas Health Science Center at San Antonio, Eloïse Dray, Daifeng Jiang, Daohong Zhou et autres
0 citationsZenodo (CERN European Organization for Nuclear Research)
Identification of sensitive and resistant genes to compound LP-184 by Genome-wide CRISPR KO screen
The University of Texas Health Science Center at San Antonio, Eloïse Dray, Daifeng Jiang, Daohong Zhou et autres
0 citationsZenodo (CERN European Organization for Nuclear Research)
Abstract 60: Discovery of Epstein-Barr Virus Antibody Seroprofiles Associated with Burkitt Lymphoma Risk in East Africa
Jacquelyn Bedsaul, Carla Proietti, Martin Ogwang, Patrick Kerchan et autres
0 citationsCancer Epidemiology Biomarkers & Prevention
Supplementary figures and tables legends from Conditional Dependency of LP-184 on Prostaglandin Reductase 1 is Synthetic Lethal in Pancreatic Cancers with DNA Damage Repair Deficiencies
Diana Restifo, Joseph McDermott, Dusica Cvetković, Troy Dos Santos et autres
0 citations
Supplementary Table 1 from Conditional Dependency of LP-184 on Prostaglandin Reductase 1 is Synthetic Lethal in Pancreatic Cancers with DNA Damage Repair Deficiencies
Diana Restifo, Joseph McDermott, Dusica Cvetković, Troy Dos Santos et autres
0 citations
Supplementary Table 2 from Conditional Dependency of LP-184 on Prostaglandin Reductase 1 is Synthetic Lethal in Pancreatic Cancers with DNA Damage Repair Deficiencies
Diana Restifo, Joseph McDermott, Dusica Cvetković, Troy Dos Santos et autres
0 citations
Supplementary Figure 2 from Conditional Dependency of LP-184 on Prostaglandin Reductase 1 is Synthetic Lethal in Pancreatic Cancers with DNA Damage Repair Deficiencies
Diana Restifo, Joseph McDermott, Dusica Cvetković, Troy Dos Santos et autres
0 citations
Supplementary Figure 1 from Conditional Dependency of LP-184 on Prostaglandin Reductase 1 is Synthetic Lethal in Pancreatic Cancers with DNA Damage Repair Deficiencies
Diana Restifo, Joseph McDermott, Dusica Cvetković, Troy Dos Santos et autres
0 citations
Supplementary Data 1 from Preclinical Efficacy of LP-184, a Tumor Site Activated Synthetic Lethal Therapeutic, in Glioblastoma
Bachchu Lal, Aditya Kulkarni, Joseph McDermott, Rana Rais et autres
0 citations
Figures 1 from Preclinical Efficacy of LP-184, a Tumor Site Activated Synthetic Lethal Therapeutic, in Glioblastoma
Bachchu Lal, Aditya Kulkarni, Joseph McDermott, Rana Rais et autres
0 citations
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