Sinead McKernan

Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT)

Nicholas I. Paton, Alejandro Arenas‐Pinto, Wendy Hadley, David Stacey et autres

Background: Treatment-simplification strategies are important tools for patient-centred management. We evaluated long-term outcomes from a PI monotherapy switch strategy. Methods: Eligible participants attending 43 UK treatment centres had a viral load (VL) below 50 copies/ml for at least 24 weeks on combination …

sg, gb, rs (code pays fourni par la source)

A highly virulent variant of HIV-1 circulating in the Netherlands

Chris Wymant, Daniela Bezemer, François Blanquart, Luca Ferretti et autres

increase (i.e., a ~3.5-fold to 5.5-fold increase) in viral load compared with, and exhibited CD4 cell decline twice as fast as, 6604 individuals with other subtype-B strains. Without treatment, advanced HIV-CD4 cell counts below 350 cells per cubic millimeter, with long-term clinical …

gb, nl, fr, se, de, ch, us, fi (code pays fourni par la source)

Irish society for rheumatology

D. Mulherin, J. A. McNally, G. Yanni, Alberto Cauli et autres

ie, us, au, kr, gb (code pays fourni par la source)