Ryan F. Donnelly

Corrigendum to “Liposome-loaded polymeric microneedles for enhanced skin deposition of rifampicin” [Int. J. Pharm., 646 (2023) 123446]

Qonita Kurnia Anjani, Anjali Pandya, Sara Demartis, Juan Domínguez-Robles et autres

gb, it, es, co, in (code pays fourni par la source)

Corrigendum to “Development and characterisation of novel poly (vinyl alcohol)/poly (vinyl pyrrolidone)-based hydrogel-forming microneedle arrays for enhanced and sustained transdermal delivery of methotrexate” [Int. J. Pharm. 586 (2020) 119580]

Ismaiel A. Tekko, Gaoyun Chen, Juan Domínguez‐Robles, Raghu Raj Singh Thakur et autres

sy, gb, jo (code pays fourni par la source)

Antifungal drug-loaded ionic liquid-in-water emulsion for nail fungal infections

Jiawen Wang, Yaocun Li, Ross Duncan, Deepa Chaturvedi et autres

Onychomycosis is a prevalent and therapeutically challenging fungal infection, largely due to the highly keratinised nail plate that severely restricts drug penetration. Voriconazole (VCZ) is a broad-spectrum antifungal agent; however, its poor aqueous solubility and limited permeability hinder its use in topical …

gb, pt (code pays fourni par la source)

Transdermal delivery of biologics

Lalitkumar K. Vora, B.H. Jaswanth Gowda, Jordan Strauss, Akeemat Tijani et autres

Biologics, including peptides, proteins, antibodies, vaccines and nucleic acid-based therapeutics, have transformed the management of chronic, metabolic, inflammatory, oncological and infectious diseases. Despite their clinical success, their wider use remains constrained by invasive administration routes, poor patient acceptability and formulation challenges related …

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Nickel Nanoparticle/Boron-Doped Diamond Nanoparticle Composite Integrated with Microneedle for Ciprofloxacin Electrochemical Detection

Qisty Saufa Alif, Prastika Krisma Jiwanti, Mirza Ardella Saputra, Qonita Kurnia Anjani et autres

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3D-printed long-acting implants for risperidone delivery using VAT photopolymerisation: a potential alternative for schizophrenia treatment

Camila J. Picco, Emilia Utomo, Elizabeth R. Magill, Qonita Kurnia Anjani et autres

Chronic conditions are increasingly prevalent worldwide, with the oral route being the most common for drug administration. However, limitations such as low bioavailability and patient nonadherence can result in complications that affect the patient's quality of life and increase healthcare costs. In …

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Preserving the gut microbiome: hydrogel-forming microneedle delivery of tetracycline reduces gut microbiome disruption compared to oral administration

Stephen A. Kelly, Li Zhao, Jonathan Nzakizwanayo, Aoife M. Rodgers et autres

Antibiotics cause significant gut microbiome dysbiosis, particularly when administered orally. This contributes to antimicrobial resistance (AMR) and is associated with myriad health conditions. Novel drug delivery strategies that minimize gut exposure while maintaining therapeutic efficacy are urgently needed. This study aimed to …

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Ultrafast-dissolving voriconazole-cyclodextrin complex-based ocular microneedle patch: a novel approach for the treatment of fungal keratitis

B.H.Jaswanth Gowda, Anjali Pandya, Shilpkala Gade, Ross Duncan et autres

Fungal keratitis (FK) is a leading cause of corneal blindness worldwide. Although voriconazole (VOR) is effective, its poor corneal permeability limits its topical use, whereas intrastromal injections are invasive and risky. Over the past 9 years, dissolving microneedle array patches (dMAPs) has …

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Corrigendum to “Dynamics of insertion and extraction of hollow pyramidal microneedles: experiments and numerical modelling” [Int. J. Pharm. 682 (2025) 125989]

Rahul Nadda, Diganta Bhusan Das, Tahir Emre Yalcın, Abraham M. Abraham et autres

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Transdermal ropivacaine delivery via hydrogel-forming microneedles: A pain-free alternative for local anaesthesia

Andang Miatmoko, Qonita Kurnia Anjani, Rifda Tarimi Octavia, Natalia Porfiryeva et autres

id, gb, kr (code pays fourni par la source)

Microneedle array platforms for drug delivery and biomarker sensing: From skin mechanics guided design to scalable manufacture for clinical utility

Jiachi Zhou, Lei Wu, Minna Wyttenbach, Ray Lennon et autres

Microneedle (MN) devices provide a platform for development of products that can facilitate intra-and trans-dermal delivery and sampling of active pharmaceutical ingredient (APIs) and biomarkers that would otherwise be restricted by the skin barrier. Despite significant progress in the development of laboratory-based …

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Integrating experiments, numerical simulations and Bayesian optimisation to maximise drug permeability of hollow pyramidal microneedle arrays

Ravi Prakash, Rahul Nadda, Abraham M. Abraham, Tahir Emre Yalcın et autres

This study presents an experimental–numerical framework integrated with Bayesian optimisation (BO) for the design of hollow pyramidal microneedle (MN) arrays to enhance transdermal drug permeability across the skin. Finite element (FE) simulations have been carried out to model coupled fluid flow and …

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